i think humanity is causing a lot of its own death (wars, overpopulation, ostracism, murder, contributions rather than opposition to climate change) but extinction? not sure. i think it is unlikely that these things would entirely wipe out mankind

I have a feeling that we're likely to survive (as a species) even the worst wars imaginable for perpetuity. Similarly, we're likely to evade or somehow mitigate the worst portions of natural disasters as well. I have a feeling that even if our population is repeatedly reduced significantly, we're going to keep coming back.

As such, barring a technological correction/workaround, or the adaptation of another chromosome to co-opt the functions tied to male fertility, our extinction will most likely be caused by the degeneration of the y chromosome (as most of it does not recombine with anything) over the course of generations eventually rendering us infertile.

Nope,humanity coming to an end,it sounds absurd after more than 4000 years of its commencement and extinction seems quite far fetched

No matter how hard we try, we, like bacteria and viruses, appear to be able to mutant to a point where we have become indestructible. We inhabit the wastelands of the frozen north and the world's burning deserts. No other species is so adaptable. It looks like all the other life forms on earth will have to endure us as we contaminate and displace them from their environments.

Humans raise thousands of unsustainable animals, deplinish soil fertility, destroy the ozone layer, and genetically alter and over populate species. But even through all this stupidity, waste, and pollution, the fact still stands that the human race has the ability to survive and adapt. Even if some kind of incredible bomb went off, I still think the human race, that is, those who somehow survived, would make it. Adaptation is human nature.