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Lortab is a prescription medication that combines two active ingredients: hydrocodone and acetaminophen. Hydrocodone is an opioid pain reliever, while acetaminophen is a non-opioid pain reliever and fever reducer. Lortab is primarily used to relieve moderate to severe pain.Hydrocodone, the opioid component of Lortab, works by binding to opioid receptors in the brain and spinal cord, which reduces the perception of pain. Acetaminophen enhances the pain-relieving effects of hydrocodone and also helps reduce fever.
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